The purpose of this paper is to compare the assessment of OSH management effectiveness in various size enterprises (micro, small and medium-sized, large enterprises). In the paper the results of research conducted among employees of enterprises from the manufacturing sector have been presented. The survey form were developed based on the interpretation of the safety management principles in analogy to the principles of quality management. It has been stated that the safety management in large enterprises usually work properly. Whereas in micro, small and medium-sized enterprises the safety management are completely unapplied and occupational safety issues (regulation, principles e.t.c.) are not treated properly. In micro-enterprises is often lack of health and safety policies, and employee knowledge in this area are negligible.